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UID:DSC-22894
DTSTART;TZID=Europe/Berlin:20260526T150000
SEQUENCE:1779773776
TRANSP:OPAQUE
DTEND;TZID=Europe/Berlin:20260526T160000
URL:https://dresden-science-calendar.org/calendar/de/detail/22894
LOCATION:MPI-CBG\, Pfotenhauerstraße 10801307 Dresden
SUMMARY:Baskin: Engineering the Chemistry of Cellular Membranes
CLASS:PUBLIC
DESCRIPTION:Speaker: Jeremy Baskin\nInstitute of Speaker: Department of Che
 mistry and Chemical Biology and Weill Institute for Cell and Molecular Bio
 logy\, Cornell University\, Ithaca\, New York\, USA\nTopics:\n\n Location:
 \n  Name: MPI-CBG (MPI-CBG CSBD SR Top Floor (VC))\n  Street: Pfotenhauers
 traße 108\n  City: 01307 Dresden\n  Phone: +49 351 210-0\n  Fax: +49 351 
 210-2000\nDescription: Cellular  membranes  are  dynamic  chemical  system
 s  whose  lipid  composition  is  tightly regulated  across  space  and  t
 ime\,  yet  the  mechanisms  governing  lipid  metabolism\, transport\,  a
 nd  function  remain  incompletely  understood.  I  will  describe  our  e
 Korts  in synthetic lipid biology to develop chemical and optogenetic appr
 oaches for interrogating membrane  function  in  living  cells.  These  in
 clude  activity-based  imaging  strategies  for visualizing  lipid  metabo
 lism  and  transport\,  photoaKinity  lipid  probes  for  mapping  lipid i
 nteractomes  and  uncovering  hidden  biological  functions\,  and  optoge
 netic  membrane editing technologies that enable rapid and spatially preci
 se manipulation of membrane lipid composition. By integrating these approa
 ches with proximity labeling\, chemoproteomics\, and  advanced  imaging\, 
  we  are  beginning  to  reveal  new  mechanisms  governing  lipid homeost
 asis\,  inter-organelle  communication\,  and  the  spatiotemporal  organi
 zation  of membrane metabolism and transport. More broadly\, these studies
  highlight how engineered chemical  tools  can  provide  new  insight  int
 o  the  architecture  and  function  of  cellular membranes.
DTSTAMP:20260610T001255Z
CREATED:20260513T053852Z
LAST-MODIFIED:20260526T053616Z
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