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UID:DSC-20729
DTSTART;TZID=Europe/Berlin:20240411T110000
SEQUENCE:1712900414
TRANSP:OPAQUE
DTEND;TZID=Europe/Berlin:20240411T120000
URL:https://dresden-science-calendar.org/calendar/en/detail/20729
LOCATION:MPI-CBG\, Pfotenhauerstraße 10801307 Dresden
SUMMARY:Daumke: Structural insights into crista junction architecture
CLASS:PUBLIC
DESCRIPTION:Speaker: Oliver Daumke\nInstitute of Speaker: MDC Berlin\nTopic
 s:\n\n Location:\n  Name: MPI-CBG (MPI-CBG Auditorium (big half))\n  Stree
 t: Pfotenhauerstraße 108\n  City: 01307 Dresden\n  Phone: +49 351 210-0\n
   Fax: +49 351 210-2000\nDescription: Mitochondrial architecture is charac
 terized by an extended and elaborately folded inner mitochondrial membrane
  (IMM). Due to their spatial constraints and specific protein inventory\, 
 the cristae domains of the IMM shape a unique micro-compartment optimized 
 for oxidative phosphorylation. Crista junctions (CJs) form the highly curv
 ed neck regions of cristae and have been suggested to act as selective ent
 ry gates into the cristae space. The mitochondrial contact site and crista
 e organizing system (MICOS) constitutes the backbone scaffold of CJs\, but
  molecular insights have remained sparse due to a lack of structural infor
 mation. Here\, I provide an overview on our efforts to characterize struct
 ure and function of crista junctions using an integrative structural biolo
 gy approach.
DTSTAMP:20260427T174346Z
CREATED:20240323T063850Z
LAST-MODIFIED:20240412T054014Z
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