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UID:DSC-22896
DTSTART;TZID=Europe/Berlin:20260518T103000
SEQUENCE:1778823401
TRANSP:OPAQUE
DTEND;TZID=Europe/Berlin:20260518T113000
URL:https://dresden-science-calendar.org/calendar/en/detail/22896
LOCATION:MPI-CBG\, Pfotenhauerstraße 10801307 Dresden
SUMMARY:Mabuchi: Liquid crystal-like ordering drives the assembly of highly
  ordered centrosomal structures
CLASS:PUBLIC
DESCRIPTION:Speaker: Akira Mabuchi\nInstitute of Speaker: The University of
  Tokyo\nTopics:\n\n Location:\n  Name: MPI-CBG (MPI-CBG CBG Galleria)\n  S
 treet: Pfotenhauerstraße 108\n  City: 01307 Dresden\n  Phone: +49 351 210
 -0\n  Fax: +49 351 210-2000\nDescription: Cells often face the challenge o
 f rapidly assembling large intracellular structures at defined times and l
 ocations. Liquid–liquid phase separation has emerged as a key mechanism 
 for such spatiotemporal organization by locally enriching specific molecul
 es. However\, certain cellular structures require more than local enrichme
 nt: their components must also adopt defined molecular orientations. How s
 uch orientational order emerges remains poorly understood. Here\, we addre
 ss this question by using the assembly of highly ordered centrosomal struc
 tures as a model system. We found that a core component of these structure
 s not only forms liquid-like condensates\, but also acquires liquid crysta
 l-like orientational order within them. I will discuss how these two modes
  of self-organization may cooperate to drive the rapid assembly of ordered
  intracellular structures.
DTSTAMP:20260515T212803Z
CREATED:20260514T053952Z
LAST-MODIFIED:20260515T053641Z
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